Description

Tapentadol Aspadol 200mg

Tapentadol, marketed as Aspadol 200 mg, is a prescription medication used to manage moderate to severe chronic pain, typically when other painkillers are not sufficient. The 200 mg tablet is usually an extended-release formulation, designed to provide pain relief over a longer period. It is generally taken twice daily, approximately every 12 hours, with or without food. It is important not to crush or chew the tablet because it is formulated to release the medicine gradually.

The dose is carefully adjusted by a doctor based on pain severity and individual tolerance. While some patients may start with lower doses such as 50 to 100 mg twice daily, doses can be increased under medical supervision up to 200 mg twice daily if necessary. The maximum daily dose is usually around 500 to 600 mg. If a dose is missed, it should be taken as soon as possible unless it is close to the next scheduled dose, in which case the next dose should be taken at the regular time without doubling up.

Important: Dosage must always be prescribed by a doctor and tailored to the patient’s pain level, health, and previous opioid use.

Typical adult doses

• Mild to moderate pain: Often starts at 50 mg every 4–6 hours as needed.

• Moderate to severe pain: May increase to 100–150 mg every 12 hours (extended-release forms exist for chronic pain).

Maximum daily dose

• Usually 600 mg per day for adults. Exceeding this can lead to serious side effects, including respiratory depression.

How to take

• Swallow tablets whole with water; do not crush or chew extended-release forms.

• Can be taken with or without food.

Timing

• Immediate-release: taken every 4–6 hours for breakthrough pain.

• Extended-release: taken every 12 hours for ongoing chronic pain.

• Do not double up doses if you miss one; follow your doctor’s instructions.

Interactions

• Sedatives, alcohol, benzodiazepines – increase risk of drowsiness or respiratory depression.

• Other opioids – can enhance sedation and risk of overdose.

• Antidepressants or MAO inhibitors – may interact with norepinephrine action.

Safety Precautions

• Avoid driving or operating machinery until you know how the medicine affects you.

• Store in a secure place to prevent misuse or accidental ingestion, especially by children.

• Do not stop suddenly if you have been using it regularly; consult your doctor for a tapering schedule to avoid withdrawal symptoms.

Side Effects to Watch

Common:

• Nausea, vomiting

• Drowsiness, dizziness

• Constipation

• Sweating

Serious (seek urgent help):

• Slow or difficult breathing

• Severe drowsiness or fainting

• Swelling or rash (allergic reaction)

• Signs of overdose: pinpoint pupils, extreme drowsiness, unresponsiveness